Tirzepatide Calculator

Also known as: Zepbound, Mounjaro

A dual GIP and GLP-1 receptor agonist for weight management and glycemic control.

For research/educational purposes only. Not medical advice. Consult a licensed physician before use.

Reconstitution Calculator

5mg
10mg
15mg
30mg
Concentration
5.00 mg/mL
Volume to Draw
0.500 mL
U-100 Insulin Syringe
50 units

How to Reconstitute

  1. Wipe the top of the peptide vial and the bacteriostatic water vial with an alcohol swab.
  2. Draw exactly 2mL of air into a large syringe (18-22G needle recommended) and inject it into the bacteriostatic water vial.
  3. Draw out exactly 2mL of bacteriostatic water.
  4. Insert the needle into the peptide vial. Angle the needle so the water runs slowly down the inside glass wall of the vial. Do not squirt it directly onto the powder.
  5. Remove the syringe. Gently swirl the vial in a circular motion until the powder dissolves completely. Never shake the vial.

Storage Guide

Unreconstituted (Powder)

2-8°C (36-46°F) refrigerated.

Reconstituted (Liquid)

2-8°C (36-46°F) refrigerated for up to 28 days.

Never freeze. Protect from light.

Injection Guide

Needle

30-31G, 8mm, 1mL (U-100) insulin syringe for injection. 18-22G for drawing water.

Injection Sites

  • Abdomen (2 inches away from navel)
  • Front of thighs
  • Back of upper arms

Rotate injection sites weekly.

Technique

Pinch skin, insert needle at 45-90 degrees, inject slowly. No aspiration needed for subQ.

Typical Titration Schedule

TimelineDose
Weeks 1-42.5mg / week
Weeks 5-85.0mg / week
Weeks 9-127.5mg / week
Weeks 13-1610.0mg / week
Weeks 17-2012.5mg / week
Weeks 21+15.0mg / week (maintenance)

Research & Citations

Tirzepatide Once Weekly for the Treatment of Obesity (SURMOUNT-1)
NEJM • 2022
SURMOUNT-3
PMC • 2023
Tirzepatide vs Semaglutide (head-to-head)
NEJM • 2025
For research/educational purposes only. Not medical advice. Consult a licensed physician before use.